STEM-Talk: Dom D’Agostino discusses advances in ketogenic metabolic therapies and hyperbaric oxygen therapies

Dr. Dominic D’Agostino, who over the past 10 years has been a frequent guest on STEM-Talk, returns to the podcast to discuss his recent research into ketogenic metabolic therapies, ketone supplements and hyperbaric oxygen therapy for traumatic brain injuries.

Dom is a Senior Visiting Research Scientist at IHMC as well as an Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida’s Morsani College of Medicine.

In addition to developing and testing metabolic-based therapies, Dom’s lab at South Florida also investigates seizure disorders, brain cancer, neurodegenerative diseases and rare genetic-metabolic disorders.

In episode 196, which is now available on your favorite podcast apps, YouTube and IHMC’s website, STEM-Talk co-hosts Drs. Ken Ford and Dawn Kernagis, have a discussion with Dom about:

— The science of ketogenic metabolic therapy (KMT) as a dietary approach to improve metabolic health.

— His work with the Moffitt Cancer Center focusing on KMT as a way to enhance immune-based therapies for certain types of cancers.

— The potential of KMT to treat high-grade gliomas, or brain cancers, such as glioblastoma, which is the most aggressive primary brain tumor in adults.

— The mitochondrial stem cell connection theory (MSCC), which argues that cancer originates from chronic oxidative phosphorylation insufficiency in stem cells

— The long-term hepatic safety of ketone supplements.

— The effects of ketone supplements on liver function.

— A paper he co-authored that showed a small amount of carbohydrates is sufficient to fuel athletic performance.

— A University of South Florida trial on hyperbaric oxygen therapy as a treatment for traumatic brain injury.

— Emerging applications of hyperbaric/hyperbaric-oxygen therapy in the treatment of different neurological disorders.

STEM-Talk is an award-winning podcast from the Florida Institute for Human and Machine Cognition that hosts conversations with the leading minds in science and technology. Listen on your favorite platform or browse our library at IHMC.us/stemtalks.