Evening Lectures - Ocala

Mark Lupo

THE TALK: Individualizing Care for Thyroid Nodules & Cancer

May 30, 2024

Abstract

Thyroid nodules are quite common – approximately 50% of adults have a nodule or cyst detectable by thyroid ultrasonography. They usually cause no symptoms nor impact thyroid function but 5-10% are malignant. The goal of thyroid nodule evaluation is to accurately identify cancer while avoiding over-treatment. There have been many advances in the last decade in ultrasound risk stratification of nodules for better selection of biopsy. Benign and malignant cytology results are highly accurate, however 15-20% of nodules are indeterminate and may benefit from further risk evaluation with molecular testing to determine if surgery is required.

Benign nodules can usually be monitored with ultrasound but sometimes grow and cause symptoms such as trouble swallowing or choking. In these cases, historically surgery has been offered but recently thermal ablation with radiofrequency or laser has become available in the USA.

Thyroid nodule and cancer management has transformed from a “one size fits all” approach to a “less is more” personalized paradigm resulting in better outcomes and patient satisfaction.

Biography

Dr. Lupo is the founder and medical director of the Thyroid & Endocrine Center of Florida located in Sarasota. He is board certified in Endocrinology and Internal Medicine. He attended Duke University then received his medical degree and internal medicine training at the University of Florida. He completed endocrine fellowship through a combined program at UC San Diego and Scripps Clinic. His endocrine practice is limited to thyroidology with an emphasis on nodules and cancer as well as autoimmune thyroid disease. He is active in teaching other physicians neck sonography, ultrasound-guided biopsy techniques and thyroid nodule/cancer management. He is also an active member of the American Thyroid Association, Endocrine Society, American Institute of Ultrasound in Medicine, and Mensa. He has published book chapters and several articles in the field of thyroidology. The Thyroid & Endocrine Center has been involved in clinical trials on thyroid nodule evaluation, autoimmune thyroid disease, and lab testing. He is on the faculty of the Florida State University College of Medicine as Clinical Assistant Professor.

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