Evaluating Potential Benefits of Intranasal Oxytocin on Undersea Operator Training and Performance: Hyperoxic Swim-Induced Oxidative Stress and Inflammation

Study Description/Summary: This study will test whether intranasal oxytocin will mitigate attenuate system and skeletal muscle stress and inflammation induced by a resistance swim and exposure to elevated oxygen levels simulating undersea military operation. Over a 12-14 day period, subjects will attend 7 laboratory visits, utilize oxytocin or placebo, and perform one resistance exercise swim.

Compensation: $1,000.

Time Commitment: Seven lab visits over a 12-14 day period.

Eligibility Criteria:

  • Recreationally Skilled Swimmer
  • Healthy male
  • 18-39 years/age
  • Non-smokers
  • No chronic conditions which prohibit exercise
  • There are a number of exclusion criteria, to ensure your safety. To inquire for a full list of these conditions and situations please fill out the form below.
cold water

Please fill out the form below if you are interested in participating in this study and meet the eligibility requirements. A member of our team will reach out to you with more details.

You can choose not to participate. Your participation is voluntary. Your participation will have no influence on anything that falls outside of this research context. A decision to not participate will involve no penalty or loss of benefits to which you are otherwise entitled, and you may discontinue participation at any time and for any reason. If you do decide to participate, you may withdraw from this study at any time and for any reason. Risks of participation do not exceed those of daily living. The risks to you as a participant are discomfort from sampling and hypoxia exposure. Although unlikely, there is always a risk for loss of confidentiality and anonymity when participating in research. All efforts will be made to protect your rights. Because the test will require multiple blood samples from the participants, although very unlikely, a risk of disease transmission exists. There is also a risk of bruising or bleeding of the skin at the sample site. Study staff will take every effort to minimize any risk associated with blood sampling. Participants can withdraw from the study at any time without penalty. Participation in this study may lead to improvements in performance, recovery, mood, arousal, or cognition.